Abstract Background Small cell lung cancer (SCLC) is an aggressive neuroendocrine cancer with an appalling overall survival of less than 5% (Zimmerman et al. J Thor Oncol 14:768-83. 2019). Patients typically respond to front line platinum-based doublet chemotherapy. https://www.rxkaitori.com/product-category/emergency-leds/
MYC drives platinum resistant SCLC that is overcome by the dual PI3K-HDAC inhibitor fimepinostat
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